I stayed at Hotel Tomo three nights for my work-related trip and would definitely stay here again. First of all, the location is excellent. The hotel is located in the heart of Japantown, which is a great combination of interesting and safe. The restaurants and shops are plenty and good: definitely worth exploring. It is also blocks away from the stylish Filmore street where you can find excellent restaurants, bars and upscale boutiques. BART and many of the areas' most popular tourist attractions are a short bus ride away.
Second, Hotel Tomo has large, clean rooms. The king-bed room that I stayed in was large enough to accommodate two adults comfortably and came with a good-size bathroom (unlike those tiny little ones found in many of the SF hotels), plenty of workspace, and FREE in-room wifi (for which many other hotels charge an exorbitant fee). The room was clean when I checked in. On one of the days of my stay, the maid did a sloppy job of cleaning it, but it was good the rest of the time. The decor of the room and the hotel is fun and quirky. If you are a fan of anime/manga, you will love it. If you prefer a more "traditional" hotel decor, you might feel a bit puzzled at staying at a room that is decorated like a bedroom of a Japanese teenager. I personally liked it. Although I am far from a teenager by decades, it was nice to stay in a room that felt more like a bedroom in a home than an impersonal/bland hotel room, especially when it had all the comforts of a hotel.
Third, the value is great. It was cheaper than the B&B (as lovely in a vintage-sort of way as it was) I stayed at in my last trip! The restaurant in the hotel serves both "American" and Japanese breakfast options at a reasonable price (I enjoyed the Japanese option, which was excellent).
Fourth, the staff at the hotel were efficient and attentive. To me, this is important.
One tip: Although the hotel offers parking ($25 plus parking tax), you can park your car at the nearby Japan Center parking lot for much cheaper ($19, including the tax). I didn't find out about this until the last day, but now you know!
Some of the rooms have balconies with a good view. Mine did not have a balcony but still have a nic...
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This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC