Following pickup at your Managua hotel, board a climate-controlled vehicle for the 2-hour ride to San Jorge. As you travel, watch the lush jungle landscape out your window and listen to engaging commentary from your guide.
Upon arrival in San Jorge, transfer to a ferry for a peaceful 1-hour trip across Lake Nicaragua. Disembark when you reach Ometepe Island and begin your exploration by visiting the Ceibo Museum. Dedicated to the island's original inhabitants and its changing demographic over the years, it is home to an array of pre-Columbian artifacts.
Visit Charco Verde Nature Reserve, which contains both Concepción and Maderas Volcanoes, both over 4,000 feet (1,300 meters) high. Take a dip in cool off in the hidden pools at Ojo de Agua deep within the forest.
Take a seat at a local restaurant for an authentic Nicaraguan lunch, then visit Santo Domingo beach for some free time. Swim in Lake Nicaragua or relax on the sand before boarding the ferry back to San Jorge, then your vehicle for transportation back to your Managua hotel.