Whether you’re coming to Jacksonville for a visit to the Mayo Clinic or just for fun at the beach, your room at the Holiday Inn Express & Suites Jacksonville SE-Medical Center is your personal retreat. Our hotel is the closest hotel located off of the Mayo Clinic Campus at just three miles away. You’ll have room to work with our oversized guest rooms and free high-speed wired or wireless Internet or you can lounge in your room and watch our large screen HDTV’s. We’re located close to the St. John’s Town Center offering the best shopping/dining in Jacksonville! The hotel is minutes away from Jacksonville Beach and Ponte Vedra, which is home to the TPC PGA Sawgrass where the annual Player’s Championship is hosted. We are conveniently located on the 15th hole of the Windsor Parke Golf Course, ask us about our Golf Rate!