There is no way to visit Florence without seeing the Duomo. It towers over the city, looming in the background on practically every street corner: outside a train window as you approach Santa Maria Novella train station, from a terrace cafe in the historic center, and while walking down Via dei Servi. The 37,000-ton engineering marvel is unmissable.

Come (incredibly) hungry to try these foods at Florence's Mercato Centrale.

Explore the palaces, museums, gardens, and secret passageways connected to the history of the Medicis.