The historic quarter of Colonia del Sacramento, founded in 1680, evokes old Lisbon with its Portuguese-influenced architecture and winding streets. The area, located in southwestern Uruguay on the Rio de la Plata, was named a UNESCO World Heritage site in 1995. It's an easy day trip by ferry from Buenos Aires, making the beaches a popular Argentinean escape. Major sights include Iglesia Matriz, the country's oldest church, the Municipal Museum and a 17th-century port jutting into the river.

Llamas, sheep and alpacas roam the plains of Puno, a port city in southeastern Peru. Their fleeces are used to make the area’s signature textiles, which make excellent souvenirs. You’ll do a lot of walking here, as many of the streets are too steep for cars. But the climbs are worth it for the excellent views of Lake Titicaca. Take a boat to the Floating Islands or get up close and personal with the four-legged locals at a llama farm.

Cuba's top beach destination sits on a 13-mile-long peninsula with powder soft sands lapped by waters of the Kawama Channel. Resort hotels teem along the shore that U.S. celebrities and gangsters, including Capone, discovered in the 1920s. Clubs and bars provide mojitos and merriment, after long days baking on the beach, golfing, diving or deep sea fishing. Rent a scooter or hop aboard an open-air tourist train or bus to see more of this stunning spot. Caves, keys and virgin forest add to the area's allure.

The great outdoors is likely to feature prominently in any vacation to Fort Walton Beach. There are two public golf courses in Fort Walton Beach, The Oaks and The Pines, while championship courses such as the one at Regatta Bay are within easy reach. Sea anglers have the opportunity for some fine shore or boat fishing, hunting down the big game fish which populate the waters off the Florida coast. The more adventurous may wish to go surfing - or even take instruction and perform a parachute jump!