Welcome to bustling San Jose, where Silicon Valley meets Spanish history and modern edifices sit alongside meticulously restored 19th-century buildings. Such is the contrast of this city, rich in tradition and, thanks to hi-tech industry, just plain rich. Five-star hotels and fine restaurants line the streets of the restored downtown area, and the cultural scene is thriving with museums, theatre and art to rival any world-class hub. Don't miss the Tech Museum of Innovation, an exploration of Silicon Valley and its impact on the area. History buffs will relish the old mansions and can delve into the city's past at the History Museum of San Jose. Save time for a round of golf or the locals' other favourite pastime, sipping coffee and people-watching at a crowded cafe.

The first thing you need to know about Carmel: Clint Eastwood used to be the mayor, so don’t come here if you’re a hooligan. But if you’re after a romantic getaway to a seaside, art-filled village, Carmel might be perfect for you. You can even bring your dog—Carmel’s hotels, restaurants and galleries are remarkably Fido-friendly.

Who cares about a little fog (okay, a lot of fog) when there’s so much to do in San Francisco? By day, explore Fisherman’s Wharf and the Aquarium of the Bay, ride a cable car, and stroll around the Presidio; by night, have a fabulous dinner (at a Michelin-starred restaurant or a tiny place in Chinatown), then hit some of the best clubs on the West Coast.

Sausalito is just a ferry ride across the bay and offers unique tours, attractions such as “Bay Model” and “Bay Area Discovery Museum,” enchanting boutique shops, art studios and galleries and a wide selection of restaurants, outdoor cafes and bistros, many with stunning views back across the bay to the city.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Dozens of nightclubs, hundreds of restaurants and some of Mexico's best beaches await you in Puerto Vallarta. The original colonial town still shines through an endless selection of shopping, art galleries, water and land activities, and hotels. Walk the malecon (boardwalk) and just try to take it all in.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

It’s not just for spring-breakers. Cancun, with its golden beaches and perfect climate, is the premiere coastal destination in Mexico. And while there is certainly a 365-day party available for college students, resorts cater well to families and to those seeking solitude. This Yucatan paradise is also the gateway to the ruins of Tulum and Chichén Itzá.

Cuba's top beach destination sits on a 13-mile-long peninsula with powder soft sands lapped by waters of the Kawama Channel. Resort hotels teem along the shore that U.S. celebrities and gangsters, including Capone, discovered in the 1920s. Clubs and bars provide mojitos and merriment, after long days baking on the beach, golfing, diving or deep sea fishing. Rent a scooter or hop aboard an open-air tourist train or bus to see more of this stunning spot. Caves, keys and virgin forest add to the area's allure.

Cayo Coco, an island just north of mainland Cuba, has some of the world’s most gorgeous beaches—think superfine white sand and shallow, clear water. It’s popular with European travelers seeking a sunny escape at one of the island’s beach-side resorts. Snorkeling and diving are fantastic.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.

Well-priced, all-inclusive beach resorts are the norm around Puerto Plata. Take a cable car to the peak of Mount Isabel de Torres, enjoy a concert at an amphitheater facing the Atlantic Ocean, visit the 16th-century San Felipe Fortress. Explore the nearby falls of Damajagua, snorkel off the beautiful island of Cayo Arena or play a round of golf in spectacular surroundings. Then discover the neighbouring towns of Cabarete, a kite-boarding hub, and Sosúa, a picturesque beach spot.

The Dominican Republic lies in the same waters as Cuba and Puerto Rico, taking up the eastern two-thirds of the island it shares with Haiti. Offering a lush interior with a mix of caves, Victorian gingerbread houses and the lore of pirates, plus 900 miles of coastline along its brim, island highlights include riding a cable car up Mount Isabel de Torres and basking on stunning Saona Island. Oh, and did we mention the D.R. is family-friendly, has just about perfect weather and is affordable?

Among the best golf destinations in the world, Punta Cana is the very picture of leisure. Several of the courses have been designed by professional golfers, making for the perfect sort of kicked-back challenge that you want on a golfing vacation. The beaches here are simply perfect: calm, warm waters that gently lap at stretches of fine white sand. Thrill yourself with a zip-line adventure, clap along with traditional Dominican music at a cultural performance, or explore the magical lagoons of the Indigenous Eyes Ecological Park.