Located on the Rhine River near the borders of France and Germany, Basel contains the country's highest concentration of museums. The culture-centric city, site of the world's most influential art market each June, is also home to the lovely Munster Cathedral, made of red sandstone with a multi-colored tile roof. Green spaces abound, including the popular zoological gardens in the city center. Switzerland's largest site of Roman ruins, Augusta Raurica, are an easy day trip to the east.

Spread along both sides of the majestic St. John River, Fredericton combines the coziness of a small town with the world-class institutions of a city much larger than this humble capital. Tree-lined streets and suburban neighborhoods of Victorian-era homes live harmoniously alongside three universities, countless historic sites, museums, riverfront trails and restaurants featuring local and international cuisines. Fredericton also boasts a number of world-renowned festivals.

Montreal, c’est si bon! This French-speaking city is considered the cultural capital of Canada, and is a cosmopolitan celebration of Québécois style. A horse-drawn carriage ride around the cobblestone streets and grand buildings of Vieux-Montréal will give you a taste of European flavour. The Basilique Notre-Dame is a confection of stained glass, and the Plateau Mont-Royal district will delight you with its quaint boutiques and cafés. Dig in to a massive plate of poutine to fuel up for a tour of the epic Olympic Park.

Ottawa is a compact, clean, cleverly planned centre of culture and politics. And it's an ideal choice for a weekend getaway. Start downtown at the architecturally stunning National Gallery of Canada, and don't miss the Canadian Nature Museum and the National Aviation Museum. Rideau Canal offers boating in the summer and ice-skating in the winter. Gatineau Park attracts cyclists and walkers, while Byward Market blends old and new Ottawa.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

Toronto's neighbour Mississauga has more than 480 parks and woodlands for you to explore. Stroll the Waterfront Trail, rent a boat at the marina or spend a day at the racetrack. It's also called Ontario's shopping capital, with everything from shopping centres and outlet malls to picturesque village-style shopping streets.

The next time you're driving to Toronto or Niagara Falls, stop in Hamilton, where tourist traffic isn't quite so rampant. The Niagara Escarpment provides spectacular scenery, with beautiful trails and waterfalls. Visit nearby farms, orchards and vineyards, or plan your trip to coincide with Hamilton's lively fall fairs.

A cosmopolitan city known as the "cultural cradle of Canada," Winnipeg is family friendly with plenty of charm. It boasts a dazzling arts, theatre and indie music scene, as well as lip-smacking dining options to tantalize every taste bud. Experience nine acres of shopping and interactive fun at the Forks Market or explore Winnipeg’s diverse neighborhoods like the historic French Quarter and Exchange District or the boho chic Osborne Village.