Once a cozy fishing village of only a few thousand people, Bodrum has experienced a renaissance in the last half century that has transformed this once-sleepy community into one of Turkey's most popular vacation hotspots. Writers, intellectuals, artists and musicians have long called this Aegean town home, or second-home, attracting a vibrant cultural scene paralleled only by the town's nightlife. Windswept beaches and glittering waters provide the backdrop to the perfect beach getaway.

One of the most popular regions in Italy, Tuscany stretches from the Tyrrhenian Sea to the Apennines. Its main cities include Florence, Pisa, Siena, Lucca, Arezzo and Livorno. Drive between stunning sites like Florence's cathedral and Uffizi Gallery and the Leaning Tower of Pisa. Or join a bike tour and pedal past sun-baked olive groves and vineyards. Don't miss the towers of San Gimignano or serene northern hill towns. For a more modern take, hit one of Florence's hip clubs, such as Space Electronic.

With 35 miles of glorious coastline along Sardinia’s northern shore, Costa Smerelda (or Emerald Coast) was created as a getaway for the rich and famous by Prince Karin Aga Khan IV in the early 1960s. Sailing, waterskiing, scuba diving, golfing, shopping, fine dining and partying are some of the area’s best activities. Hotel prices can be exorbitant, but that’s no problem for the area’s wealthy visitors, even less so since many arrive in their own private yachts. Porto Cervo is the main town.

We hear the question, "What’s the next Prague?" a lot. But while we’re all for discovering great new destinations, we hardly think Prague is over. Sure, everyone’s heard of it, but it’s still a grand city with extraordinary historic and cultural sights, and it’s definitely worth a visit. The often-rebuilt Prague Castle has overlooked the city since the 9th century, and the synagogues and cemetery of the Jewish Quarter are must-sees. Nightlife here is diverse and plentiful, from trendy clubs to sophisticated wine bars to late-night cellar bars.