We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

We won't lie: Niagara Falls is uber-touristy. There are wax museums and a Ripley's Believe It or Not Museum, and if it's a fast-food chain, you can probably find it here. But even the most jaded hipster shouldn't pass up a chance to visit this town, because the Falls themselves are spectacular.

Named for Shakespeare's birthplace, Stratford has grown to become Canada’s premier arts town. In addition to the annual Stratford Festival, performing from April through October, Stratford is always filled with theatre, music and visual arts. The preserved 19th-century architecture and acres of parks and gardens (along its own Avon River, no less) are certain to charm. Stratford has also gained a reputation for culinary creativity, showcased at some of the finest restaurants in the country.

Buffalo is being reborn as a mecca for art, architecture, history, culture, dining and entertainment. Experience Frank Lloyd Wright’s stunning Darwin Martin House Complex and world-class modern art at the Albright-Knox Art Gallery. Relive part of the city’s incredible history at the Theodore Roosevelt Inaugural National Historic Site. Explore the emerging Canalside waterfront district, hip Elmwood Village, more than 400 independently owned restaurants (serving our famous chicken wings and more) and nearby Niagara Falls.

Ottawa is a compact, clean, cleverly planned centre of culture and politics. And it's an ideal choice for a weekend getaway. Start downtown at the architecturally stunning National Gallery of Canada, and don't miss the Canadian Nature Museum and the National Aviation Museum. Rideau Canal offers boating in the summer and ice-skating in the winter. Gatineau Park attracts cyclists and walkers, while Byward Market blends old and new Ottawa.

Anyplace can have an amazing pool and spa, but an amazing pool and spa in the middle of a gorgeous desert? That’s what you’ll find at Sedona’s resorts. If you do feel like taking a break from lounging poolside and sampling different kinds of massages, you'll find miles of trails for hiking, biking and horseback tours. Afterward, of course, you'll need another massage. It's the good kind of vicious cycle.

Although Tucson's fantastic weather, national parks and forests and desert provide the perfect environment for lots of outdoor recreational activities, this city of half a million people also has its share of history and culture. With a history that goes back much further than many of its southwestern neighbours, Tucson boasts turn-of-the-century architecture, historic neighbourhoods, museums and the Mission San Xavier del Bac, a still-functioning 18th-century mission considered one of the most beautiful in the USA. Mexican and Native American influences are pervasive, and the city has a distinctly Western flavour. There's also a college-town atmosphere, thanks to the University of Arizona, which has its own share of museums and a science centre. Whether golfing at a world-class golf resort, horse riding, hiking in the wilderness, discovering desert flora and fauna at the Arizona-Sonora Desert Museum, or exploring pre-Columbian and other art at the Tucson Art Museum, you'll have a mind-boggling array of things to do.

Scottsdale has more spas per capita than any other city in the U.S.—so whether you’re looking for the latest medi-spa technology or a new-agey, bohemian vibe, there’s sure to be something for you. It's a good thing, too—after spending all day touring the beautiful desert, you'll be grateful for some pampering.

Nearly perfect year-round weather and several impeccably designed championship courses have made Phoenix one of the world's top golf destinations. But there's more to this mild-mannered metropolis than pristine greens and tee times. The greater Phoenix area also offers an array of impressive cultural attractions. Visit the internationally renowned Heard Museum for an in-depth look at Native American history or peruse the fine collection at the Phoenix Museum of Art. Enjoy a ballet performance at the ornate Orpheum Theater, or catch a Broadway show at the state-of-the-art Dodge. In addition to golf, the city offers numerous outdoor activities including rock climbing, hot-air ballooning, desert jeep tours and more. Family-friendly attractions, first-rate shopping, dining and entertainment, and spectacular recreational activities make Phoenix a must-see destination.

What happens when a "gassy" Englishman rows into town feeling thirsty? A pub is born. And from that a city—in this case Vancouver. Though the pubs are plentiful, food and drink aren’t the only things to take in during your trip. In its 150 years, Vancouver has grown into a cosmopolitan city nestled in the great outdoors. Enjoy the snow-capped mountains, waterfront forests, cityside beaches, Olympic history and the world’s highest suspension bridge. Hipsters welcome. (Don’t worry, they don’t bite.)