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Mark Twain Brewing Company

422 N Main St, Hannibal, MO 63401-3324
+1 573-406-1300
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  • Excellent29%
  • Very good39%
  • Average19%
  • Poor8%
  • Terrible5%
Travellers talk about
“burger” (54 reviews)
“apricot wheat” (8 reviews)
“wings” (23 reviews)
Closed Now
American, Bar, Pub, Brew Pub
$$ - $$$
422 N Main St, Hannibal, MO 63401-3324
All Details
Write a ReviewReviews (467)
Traveller rating
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1 - 10 of 465 reviews

Reviewed 1 week ago via mobile

Entrance is deceiving because it's nearer the river ( away from the street) Nice selection of beer ( try a flight). Barbeque tacos were delicious. Try and sit upstairs for a view of the river but there is live music downstairs. Fun place!

Thank mollywan
Reviewed 1 week ago

The brewery is located right on the Mississippi, and the outdoor tables on the balcony offer a wonderful view of the river and the river traffic. This building used to house a Model T car factory, but after several intermediate owners, it was converted into...More

Thank Gabriel H
Reviewed 1 week ago

The place is kinda funky on the inside. It was a building that was converted into a restaurant. It has a different feel than the average restaurant location. The service was stellar the food was excellent.

Thank frequenttravelerdave
Reviewed 1 week ago

Not all our meals were the most amazing, but everything was better than average. Our waitress took forever in getting back to us. I went to the bar to get my glass of wine. Must have been busier than normal. Wings were really good.

Thank jfs6
Reviewed 1 week ago

Local music, local brews and meat smoked on site. Food was good, beer was great. Love to see an old building being repurposed. Once single women sitting at bars get the same service as guys, there will be more 5 star reviews.

Thank Equinepro42
Reviewed 3 weeks ago via mobile

We were pleasantly surprised after reading reviews. We had the wings, fried portobello mushrooms, chili dog and fries. Topped it off with Habanero Apricot beer (which was awesome!) we would definitelyretuen

Thank lourdesmomma
Reviewed October 14, 2018 via mobile

Looking forward to our next visit! Friendly staff, good food, and very good beer! Bought some cool beer glasses too.

Thank NorthwoodsJuan
Reviewed October 3, 2018

Stopped in for a beer and appetizer in afternoon (beer cheese and cruncher potato chips, yummy) Went back for dinner. Got smoked chicken with onion rings and green beans and potatoes. Onion rings were frozen but very crispy. Chicken was good with just a little...More

Thank buckmi
Reviewed October 3, 2018

Wonderful atmosphere. Staff was very nice, music playing was great. Beer was good - I recommend the Jalapeño-Peach. Yum. Sweetness going down,then BANG, the jalapeño hits. Nachos were interesting, but very dry. I wouldn't really call them nachos.

Thank tingodmusic
Reviewed October 2, 2018 via mobile

Nice little place close to the river in scenic downtown Hannibal Missouri. While the decor was nice and the microbrews were on tap, the food was expensive and touristy. To be expected in this area, just a little disappointing. Take time and visit the rest...More

Thank Mdaddy46
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Ask a question
Questions & Answers
July 31, 2018|
AnswerShow all 3 answers
Response from Dave A | Property representative |
David F
April 19, 2018|
AnswerShow all 7 answers
Response from Jason G | Property representative |
Yes, we have an extensive wine list and several local Missouri wines options as well. We have a full bar with a bourbon, scotch, and wine list.
Sierra H
September 23, 2017|
AnswerShow all 8 answers
Response from Dave A | Property representative |
Yes, we have a kids menu.
Improve this listing

Restaurant Details

Rating summary
  • Food
  • Value
American, Bar, Pub, Brew Pub
Lunch, Dinner
Restaurant features
Takeout, Outdoor Seating, Seating, Waitstaff, Parking Available, Television, Highchairs Available, Wheelchair Accessible, Serves Alcohol, Full Bar, Free Wifi
Good for
Bar Scene, Child-friendly, Kids, Special Occasion Dining, Local cuisine, Groups
Open Hours
12:00 a.m. - 9:00 p.m.
11:30 a.m. - 10:30 p.m.
11:30 a.m. - 10:30 p.m.
11:30 a.m. - 10:30 p.m.
11:30 a.m. - 11:00 p.m.
11:30 a.m. - 11:00 p.m.
Location and Contact Information
  • Address: 422 N Main St, Hannibal, MO 63401-3324
  • Location: United States  >  Missouri (MO)  >  Hannibal
  • Phone Number: +1 573-406-1300
  • E-mail
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