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Rx Restaurant and Bar

Certificate of Excellence
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421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
17:00 - 22:00
Closed now
See all hours
Sun 10:00 - 22:00
Tue - Thu 17:00 - 22:00
Fri - Sat 17:00 - 22:30
More Info
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200 Reviews from our TripAdvisor Community

Traveller rating
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Time of year
Showing 199: English reviews
Charlotte, North Carolina
Level Contributor
67 reviews
46 restaurant reviews
common_n_restaurant_reviews_1bd8 4 helpful votes
Reviewed 1 week ago

A friend's friend recommended we all meet there for Sunday Brunch. I googled the menu and found some strange sounding menu items. Once there, it was a quaint place with pleasant surprises. Pork belly was bacon, for example. The mini biscuits were excellent! The way they did shrimp and grits was outstanding. The server was attentive and cheery without being... More 

Thank Andra' E
Level Contributor
55 reviews
24 restaurant reviews
common_n_restaurant_reviews_1bd8 14 helpful votes
Reviewed 12 March 2017 via mobile

We had brunch and the food was really good. My french toast topped with blueberries was wonderful! Great variety of food on the menu - sure to please everyone in your group! Nice atmosphere and good service as well.

Thank TravelerKay
Tryon, North Carolina
Level Contributor
60 reviews
48 restaurant reviews
common_n_restaurant_reviews_1bd8 32 helpful votes
Reviewed 11 March 2017

Our first visit to Rx Restaurant and Bar. It was a weekday evening and the place was pretty busy, even at our 8:00pm reservation time. Friendly and caring staff, they went above and beyond to make our experience the best they could. The wine list is varied, something for every palate and price point, supplemented by excellent and knowledgeable advice... More 

1 Thank Roger S
Wilmington, NC
Level Contributor
20 reviews
15 restaurant reviews
common_n_restaurant_reviews_1bd8 17 helpful votes
Reviewed 6 March 2017

Make sure to get a reservation. Delicious food, perfectly prepared. Nice size portions. Only negative is the decor

Thank happyWilmington_NC
Leland, North Carolina
Level Contributor
213 reviews
130 restaurant reviews
common_n_restaurant_reviews_1bd8 44 helpful votes
Reviewed 22 January 2017 via mobile

Recently went here with visiting family members without knowing anything about the restaurant. We were not disappointed. They have a new menu every night, including interesting cocktail options. The night we were there they had five entree options with a variety of ingredients. Nice, comfortable neighborhood feel with cozy bar. Pleasant service.

Thank NCTravelfan58
Level Contributor
51 reviews
26 restaurant reviews
common_n_restaurant_reviews_1bd8 35 helpful votes
Reviewed 3 January 2017

Being new to Wilmington we had heard rave reviews of Rx Restaurant and Bar. Being a fan of local farm to table and fresh ingredients we were excited to find this restaurant. We decided to try it for New Years Eve. Usually not a great night for restaurants since they are usually very busy and quality sometimes is lacking.....Well, let... More 

Thank Floridawillsgirl
Vienna, Virginia
Level Contributor
17 reviews
13 restaurant reviews
common_n_restaurant_reviews_1bd8 12 helpful votes
Reviewed 3 January 2017

Meal was very good.... Table choices included the two layer chicken and fish. Service was very good and accommodating as we worked through the wine selections... Definitely order the pig ears as an appetizer. If you are visitng Wilmington this is a not to be missed restaurant

Thank Ecanv
Wilmington, NC
Level Contributor
102 reviews
77 restaurant reviews
common_n_restaurant_reviews_1bd8 53 helpful votes
Reviewed 30 December 2016 via mobile

Great food and very generous Main course portions. We had excellent service loved all the food. We had steak, duck and trout and all the entrees were well prepared, flavorful and generous. The desserts were equally good. We had the Swiss roll and the apple cake. The apple cake definitely was the crowd favorite. All in all a very fun... More 

Thank bmcfeeters
Burgaw, North Carolina
Level Contributor
5 reviews
5 restaurant reviews
Reviewed 21 December 2016

While I have visited this restaurant several times over the last year or two and been generally pleased, my wife and I dined at Rx last evening and I am not really inclined to return. I understand they restaurant is shooting for the Hip, Progressive image; however, there is a thing called reserve and decorum in an establishment that patrons... More 

Thank timber2117
Wilmington, North Carolina
Level Contributor
31 reviews
18 restaurant reviews
common_n_restaurant_reviews_1bd8 10 helpful votes
Reviewed 18 December 2016

My wife and I enjoyed our Sunday brunch of Pigs Ears, Bill's Clams and Monte Cristo. Attentive and cordial service with our chatty waitress enhanced the experience. Eclectic and tasteful artwork completed the happening. We'll be back for dinner soon!

Thank john s

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Restaurant Details

Rating summary
  • Food
    4.5 of 5 bubbles
    4.5 of 5 bubbles
  • Value
    4 of 5 bubbles
    4 of 5 bubbles
Average prices
US$30 - US$30
American, Gluten Free Options
Lunch, Dinner, Brunch, After-hours
Restaurant features
Reservations, Seating, Waitstaff, Serves Alcohol, Full Bar, Wheelchair Accessible
Dining Style
Casual Elegant
Good for
Child-friendly, Special Occasion Dining, Romantic, Local cuisine, Bar Scene
Open Hours
10:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:30
17:00 - 22:30
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
Located in the old Hall's Drugstore on 5th and Castle

Questions & Answers

Here's what previous visitors have asked, with answers from representatives of Rx Restaurant and Bar and other visitors
2 questions
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Kingsport, Tennessee, United States
over a year ago
Kingsport, Tennessee, United States
over a year ago

See all questions (2)

Questions? Get answers from Rx Restaurant and Bar staff and past visitors.
Posting guidelines
Typical questions asked:
  • Do you have gluten-free options?
  • Is there a dress code?
  • Do you allow dogs on the outdoor patio?