Lake Tahoe
Rent some condos at Marriott
http://www.marriott.com/hotels/travel/rnotl-marriotts-timber-lodge/
Lots to do within walking distance; nice place; the condo also has many activities for every age range
If you are ok with rustic, Monterey.
Get some rooms at Asilomar State Park....
5 minute walk to gorgeous beach area;
lodge is in trees
you can arrange for activities like marsh mellow roasts; family dinners; get the options with breakfast included.
Lots of day activities like Monterey Aquarium, Point Lobos, shopping in Carmel, Big Sur
http://www.visitasilomar.com/accommodations.aspx
Yosemite
get some cabins/homes through Yosemite West
http://www.yosemitewest.com/
Out of state Branson, Missouri - lots of shows to go to, things to see
Marriott Branson
http://www.marriott.com/hotels/travel/sgfhb-marriotts-willow-ridge-lodge/
and many more