Will you be traveling from the airport, a hotel in Guatemala City, a hotel in Antigua? Budget? If you can afford the cost, private shuttles are wonderful - you get to pick the schedule, make planned and unplanned trips en route (Iximmché Maya site, view points, bathroom or food breaks), and ride in comfort. Cost from GC might be $100-120, less from Antigua. Here are 2 transportation providers I’ve been pleased with in Guatemala for share shuttles, private transfers, and flight arrangements:
Rainbow Travel: http://www.rainbowtravelcenter.com
Our favorite private driver, Alfredo Garcia, is bilingual, personable, prompt, and safe, and has nice vehicles; his wife Jane is a well-regarded tour guide and they can both be reached here: http://www.mayalandiatours.com/
If that's more than you want to pay, let us know your departing point so we can help you better.
You can take a shuttle (for example Adrenalina Tours, Atitrans...).
You can take a taxi or ask your hotel in Jaibalito to arrange a taxi for you.
You can go with a private driver.
Thank you so much sounds much better than bus
The above advice is good if you're traveling directly from Guatemala City to the lake, but most tourist go first to Antigua and spend a night or more before moving on to the lake. Antigua is reached easily from the airport by shared shuttle (about $10) or taxi (about $35), and it's a good place to relax after your flight, get a better feel for the country and its culture, obtain a cellphone plan, get Quetzales for the next phase of your journey, etc. From Antigua a shared shuttle to Pana will run about $15, or somewhat more for a less-crowded shuttle booked through Antigua Tours.
If I arrive at night I generally have my little hotel in Antigua arrange a driver for me. If I arrive during the day I use a share shuttle ($10-12/pp, might need to wait for the van to fill and to drop off other passengers in Antigua). Also, there are links to agencies in Post 1, above.
I have taken a shuttle van from Antigua directly to Pana several times. You can arrange to be picked up where you are staying in Antigua. Get off in Pana and then walk or take a tuk tuk to the dock area. Then you will need to take a public boat from Pana to the dock at Jaibalito. Be careful as the boats do stop around 4 or 5 pm. It's maybe 15 mins on the boat. Awkward to get in and out of the boats there.
It is really easy! Make sure to have Guat money as last time I was in Jaibalito there was no ATM.
Ask the shuttle driver to drop you off at the dock.
OK; the original post was about travel to Jaibalito in April 2018, which was promptly answered in some depth. Then there was a subsequent post to this thread in September asking about a different topic, i.e., transport to Antigua from the airport, which also was quickly answered. Now, a month later the thread has resumed with answers to the original poster, who presumably completed her travel months ago. What’s the point? [That’s rhetorical; please don’t answer.]